Physiopathologic bases of the clinical manifestations of COVID-19

Authors

Keywords:

physiopathology, clinical manifestations, COVID -19

Abstract

Introduction: The increases of cases at worldwide, the physiopathologic studies, the clinical spectrum and the appearance of new symptoms of COVID-19 have made possible a better definition.

Objective: To describe aspects related to the physiopathologic bases of the clinical manifestations of COVID-19.

Methods: An integrated revision in the data bases PubMed and Google scholar, in January, 2021 was carried out. The criteria of selection were: articles with free access to the total text, published in Spanish and English. Duplicated studies and those with low scientific quality were excluded, they were evaluated by the critical and specialized reading. 39 articles were selected as references.

Conclusions: The immune response and the storm of cytokine were two of the key physiopathologic factors that aggravate the disease. SAR-CoV-2 is a virus that causes several multi-organs disorders.

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Author Biographies

Norberto Esqueff Díaz, Hospital Materno Infantil ¨Comandante Manuel Piti Fajardo¨. Güines, Mayabeque.

Especialista de I grado en Dermatología y II grado en Medicina General Integral. Asistente. Hospital Materno Infantil ¨Comandante Manuel Piti Fajardo¨. Facultad de Ciencias Médicas de Mayabeque. Güines

Erie Rafael Roche González, Instituto de Ciencias Básicas y Preclínicas ¨Victoria de Girón¨.

Médico General Básico. Residente de Neurofisiología Clínica.

Dianelys Jacomino Fernández, Policlínico Docente “Martha Martínez Figuera”, Güines, Mayabeque.

Especialista de II grado en Medicina General Integral. Máster en Atención Integral al Niño. Profesora Auxiliar. Policlínico Docente ¨Martha Martínez Figuera¨. Facultad de Ciencias Médicas de Mayabeque. Güines.

Lidia Sánchez Gutiérrez, Policlínico Docente “Martha Martínez Figuera”.

Especialista de I grado en Medicina General Integral. Policlínico Docente ¨Martha Martínez Figuera¨. Facultad de Ciencias Médicas de Mayabeque. Güines.

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Published

2022-09-30

How to Cite

1.
Esqueff Díaz N, Roche González ER, Jacomino Fernández D, Sánchez Gutiérrez L. Physiopathologic bases of the clinical manifestations of COVID-19. Medimay [Internet]. 2022 Sep. 30 [cited 2024 Oct. 16];29(3):447-62. Available from: https://medimay.sld.cu/index.php/rcmh/article/view/1861

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Vol. 29 No. 3 (2022)

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REVIEW ARTICLES

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