Colangitis esclerosarte primaria y enfermedad de Crohn

Authors

  • Milay Bello Núñez
  • Martín Rapado Viera

Keywords:

Colangiti esclerosante primaria, cirrosis hepática, enfermedad de Crohn

Abstract

La colangitis esclerosante primaria es una enfermedad crónica del hígado de etiología desconocida caracterizada por inflamación y fibrosis del árbol biliar. Provoca una cirrosis biliar e incrementa el riesgo de colangiocarcinoma. Afecta más a hombres en la cuarta década de vida. Debuta con escasos síntomas ó con un cuadro sintomático florido. La forma primaria se asocia a enfermedades inflamatorias intestinales, en el 90 % a la colitis ulcerosa y rara vez a enfermedad de Crohn. Se presenta paciente femenina de 53 años, raza negra y antecedente de salud, que comenzó con coloración amarilla-verdosa de piel y mucosas, orinas oscuras, prurito intenso y cambios del hábito intestinal. Al examinarla se constató íctero y hepatomegalia. Se realizó diagnóstico enzimático, imagenológico, endoscópico e histopatológico de una colangitis esclerosante primaria asociada a una enfermedad de Crohn. El tratamiento medicamentoso con ácido ursodexicólico reportó beneficios, sin embargo, la paciente muere por complicaciones antes del trasplante hepático.

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References

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http://www.ncbi.nlm.nih.gov/pubmed/15094230

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Published

2013-03-10

How to Cite

1.
Bello Núñez M, Rapado Viera M. Colangitis esclerosarte primaria y enfermedad de Crohn. Medimay [Internet]. 2013 Mar. 10 [cited 2024 Dec. 22];19(1):125-30. Available from: https://medimay.sld.cu/index.php/rcmh/article/view/624

Issue

Vol. 19 No. 1 (2013)

Section

CASE REPORTS

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