Post-COVID-19 condition in SARS-CoV-2 infection
Keywords:
pandemics, COVID-19, SARS-CoV-2, post-COVID-19 conditionAbstract
Introduction:
Polemics about mechanisms that determine the persistence of symptoms in patients infected by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus, that produces the post-COVID-19 condition, have been revealed.
Objective:
To integrate information about post-COVID-19 condition in the infection by
SARS-CoV-2.
Methods:
A narrative revision related to the information about the post-COVID-19 condition in the infection by SARS-CoV-2 was performed. The searching was made, consulting the data bases Pubmed, and SciELO, without date restriction in Spanish and English. The revision included 24 researching articles, 12 revision articles, two metanalysis, and 14 editorials or commentaries.
Conclusions:
In spite of the advances in knowledge of etiology pathogen of this disease, it still requires to clear with precision the physiopathologic mechanisms of this post-COVID-19 condition, due to it is recognized that this disease can affect many systems of different organs.
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References
Guan WJ, Ni ZY, Hu Y, Hua Liang W, Ou CQ ,He JX , Liu L, et al. Clinical characteristics of Coronavirus disease 2019 in China. N Engl J Med[Internet]. 2020 [citado 15 Jul 2022]; 382(18):1708-20. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32109013/
Lambert NJ, Survivor Corps. COVID-19 long hauler. Symptoms Survey Report;2020 Jul 29; Indiana: Indiana University School of Medicine; 2020. [citado 15 Jul 2022]. Disponible en: https://scholarworks.iupui.edu/bitstream/handle/1805/25685/Lambert2020COVID-19.pdf
Office for National Statistics[Internet].The prevalence of long COVID symptoms and COVID-19 complications. Reino Unido, Segensworth Road: Office for National Statistics; 2020 [citado 23 Jun 2022]. Disponible en: https://www.ons.gov.uk/news/statementsandletters/theprevalenceoflongcovidsymptomsandcovid19complications
Gaebler C, Wang Z, Lorenzi JC, Muecksch F, Finkin S, Tokuyama M, et al. Evolution of antibody immunity to SARS-CoV-2. Nature[Internet]. 2021 [citado 23 Jun 2022];591(5871): 639–44 Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221082/
Ibarra R. El síndrome post COVID-19 incluye hasta 50 síntomas [Internet].DIARIO ABC, S.L. 2021 Feb 2; Salud Enfermedades. [citado 21 May 2022].Disponible en: https://www.abc.es/salud/enfermedades/abci-sindrome-post-covid19-incluye-hasta-50-sintomas-202102021701_noticia.html
Liang W, Feng Z, Rao S[Internet]. Olivos.
Buenos Aires, Argentina: IntraMed; c1997-2023 [citado 21 May 2022]. COVID-19 Compromiso digestivo: ¿El eslabón perdido?. Disponible en: https://www.intramed.net/contenidover.asp?contenidoid=95815
Vicente S [Internet]. Logroño, La Rioja, España: HUFFPOST; c 2020[citado 22 Mar 2022]. Qué es el síndrome de covid-19 prolongado?. Disponible en: https://www.huffingtonpost.es/entry/que-es-el-sindrome-de-covid-19-prolongado_es_5fc4c3c5c5b63d1b770da172.html
BBC News Mundo [Internet]. Brasil: BBC News Mundo; c 2020[citado 17 Feb 2021]. Secuelas del coronavirus: los pacientes que siguen sufriendo problemas tras haber superado el COVID-19. Disponible en: https://www.bbc.com/mundo/noticias-53759283
Ángeles Rivero MR. Síndrome post COVID’ podría tener graves impactos de salud y sociales. Televisa. News [internet] 2021 [citado 17 jun 2022]. Disponible en: https://noticieros.televisa.com/ultimas-noticias/sindrome-post-covid-podria-tener-graves-impactos-de-salud-y-sociales-oms/
Organización Mundial de la Salud[Internet]. Ginebra: OMS; c 2020[citado 17 Jun 2022]. Emergency use ICD codes for COVID-19 disease outbreak. Disponible en: https://www.who.int/standards/classifications/classification-of-diseases/emergency-use-icd-codes-for-covid-19-disease-outbreak
Síndrome post COVID19: efectos a mediano y largo plazo. Sanatorio Allende. La voz. 2021 [citado 22 mar 2022]. .Disponible en: https://www.lavoz.com.ar/espacio-de-marca/sindrome-post-covid19-efectos-a-mediano-y-largo-plazo/
Mayo Clinic [Internet]. Washington, DC, EE. UU. : Mayo Clinic; c 2022[citado 17 Jun 2022].COVID-19 (coronavirus): Efectos a largo plazo. Disponible en: https://www.mayoclinic.org/es-es/diseases-conditions/coronavirus/in-depth/coronavirus-long-term-effects/art-20490351
Callard F, Perego E. How and why patients made Long COVID. Soc Sci Med[Internet].2021[citado 18 Ene 2022];268: 113426. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539940/
Greenhalgh T, Knight M, A’Court C, Buxton M, Husain L. Management of post-acute COVID-19 in primary care. BMJ[Internet]. 2020[citado 18 Ene 2022];370: m3026. Disponible en: https://www.bmj.com/content/bmj/370/bmj.m3026.full.pdf
.National Institute for Health and Care Excellence (NICE), Scottish Intercollegiate Guidelines Network (SIGN), Royal College of General Practitioners (RCGP) [Internet]. Reino Unido: NICE; c2020 [citado 18 Ene 2022]. COVID-19 rapid guideline: managing the long-term effects of COVID-19. Disponible en: https://www.nice.org.uk/guidance/ng188/resources/COVID19- rapid-guideline-managing-the-longterm-effects-of-COVID19-pdf-51035515742
Noticias ONU[Internet]. Nueva York: ONU; c 2021[citado 02 Jul 2022]. Definen el síndrome post COVID-19 o “COVID-19 de larga duración” como enfermedad. Disponible en: https://news.un.org/es/story/2021/10/1498072
¿Qué es la condición post-covid?: esto dijo la OMS. Periódico Digital Centroamericano y del caribe 2021 [citado 09/07/2022]. Disponible en: https://newsinamerica.com/pdcc/boletin/2021/que-es-la-condicion-post-covid-esto-dijo-la-oms/
Qin C, Zhou L, Hu Z, Zhang S , Yang S, Tao Y, et al . Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin Infect[Internet]. 2020 [citado 11 May 2022]; 71(15): 762-8. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108125/
Chen J, Lau YF, Lamirande EW. Cellular immune responses to severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection in senescent BALB/c mice: CD4+ T cells are important in control of SARS-CoV infection. J Virol[Internet].2020[citado 12 Mar 2021];8483:1289-301. Disponible en: https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC2812346&blobtype=pdf
Shi Y, Wang Y, Shao C , Huang J, Gan J, Huang X, et al. COVID-19 infection: the perspectives on immune responses. Cell Death Differ[Internet]. 2020 [citado 12 Jun 2022]; 27(5):1451-4. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091918/pdf/41418_2020_Article_530.pdf
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet[Internet]. 2020 [citado 20 Mar 2022];395(10223):497-506. Disponible en: https://www.thelancet.com/article/S0140-6736(20)30183-5/fulltext
Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost[Internet]. 2020 [citado 20 Mar 2022]; 18(4):844-7. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166509/
Ruan Q, Yang K, Wang W, Jiang L, Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Med[Internet]. 2020 [citado 20 Mar 2022];46(5): 846–8. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080116/
Moore BJ, June CH. Cytokine release syndrome in severe COVID-19. Science[Internet].2020[citado 21 Mar 2022];368(6490):473-4.Disponible en: https://www.science.org/doi/10.1126/science.abb8925?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Otte M, Klussmann J, Luers J. Persisting olfactory dysfunction in patients after recovering from COVID-19. J Infect[Internet].2020[citado 2021 18 Mar 2021]; 81(3):e58. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313498/
Davis HE, Assaf GS, LMcCorkell L, Wei H,Low RJ, Re’em Y. Characterizing long COVID in an International cohort: 7 months of Ssymptoms and their Impact. MedRxiv[Internet].2020 [citado 21 mar 2022].27. Disponible en: https://www.medrxiv.org/content/10.1101/2020.12.24.20248802v2.full.pdf
Sociedad Española de Médicos Generales y de Familia. COVID-19 persistente. Encuesta. 2020 [citado 2 Mar 2022]. Disponible en: https://www.semg.es/images/2020/Noticias/20201111_Resul
tados_Encuesta_COVID_Persist ente.pdf
Centers for Disease Control and Prevention [Internet].Atlanta: CDC; c2020. [citado 11 Mar 2022]. What is ME/CFS? Myalgic encephalomyelitis/chronic fatigue syndrome: Information for healthcare providers. Disponible en: https://www.cdc.gov/me-cfs/about/index.html
Gorna R, MacDermott N, Rayner C, Hara M, Evans S, Agyen L, et al. Long COVID guidelines need to reflect lived experience. Lancet[Internet].2020 [citado 20 May 2022];397(10273):455-7. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755576/
Salehi S, Reddy S, Gholamrezanezhad A. Long-term Pulmonary Consequences of Coronavirus Disease 2019 (COVID-19): What We Know and What to Expect. J Thorac Imaging[Internet].2020 [citado 23 Jul 2022]; 35(4):W87-9. Disponible en: https://journals.lww.com/thoracicimaging/Fulltext/2020/07000/Long_term_Pulmonary_Consequences_of_Coronavirus.11.aspx
Vasarmidi E, Tsitoura E, Spandidos D A, Tzanakis N, Antoniou K M. Pulmonary fibrosis in the aftermath of the COVID-19 era (Review). Exp Ther Med [Internet].2020 [citado 11 May 2022]; 20(3):2557-60. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401793/
Wei J, Yang H, Lei P, Fan B, Qiu Y, Zeng B, et al. Analysis of thin-section CT in patients with coronavirus disease (COVID-19) after hospital discharge. J X-Ray Sci Technol [Internet].2020 [citado 28 Mar 2022]; 28(3):383-9. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369060/
Mo X, Jian W, Su Z, Chen M, Peng H, Peng P, et al. Abnormal pulmonary function in COVID-19 patients at time of hospital discharge. Eur Respir J [Internet]. 2020 [citado 26 Mar 2022];55(6):2001217. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236826/
Carfì A, Bernabei R, Landi F. Persistent Symptoms in Patients After Acute COVID-19. JAMA [Internet].2020 [citado 18 May 2022]; 324(6):603-5. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349096/
Guo T, Fan Y, Chen M, Xu X, Zhang L, He T, et al. Cardiovascular implications of Fatal Outcomes of Patients With Coronavirus Disease
(COVID-19). JAMA Cardiol[Internet]. 2020 [citado 21 Feb 2022];5(7):811-8.Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101506/
Mitrani RD, Dabas N, Goldberger JJ. COVID-19 cardiac injury: Implications for long-term surveillance and outcomes in survivors. Heart Rhythm[Internet].2020 [citado 21 May 2022];17(11):1984-90. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319645/
Xiong Q, Xu M, Li J, Liu Y, Zhang J, Xu Y, et al. Clinical sequelae of COVID-19 survivors in Wuhan, China: a single-centre longitudinal study. Clin Microbiol Infect[Internet].2020[citado 20 May 2021];27(1):89-95. Disponible en: https://www.sciencedirect.com/science/article/pii/S1198743X20305759
Sardari A, Tabarsi P, Borhany H, Mohiaddin R, Houshmand G. Myocarditis detected after COVID-19 recovery. European Heart journal Cardiovascular Imaging[Internet].2021[citado 20 May 2021];22(1):131-2. Disponible en: http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7574602&blobtype=pdf
Puntmann VO, Carerj ML, Wieters I, Fahim M, Arendt C, Hoffmann J, et al. Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19). JAMA Cardiol [Internet]. 2020 [citado 20 May 2022]; 5(11): 1265–73. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385689/
COLÁS J. Los nefrólogos alertan los daños renales del COVID 19. [Internet]. 2020 [citado 20 May 2022] Disponible en: https://cronicaglobal.elespanol.com/letraglobal/letras/ciencia/nefrologos-alertan-coronavirus-causa-danos-renales_355656_102.html
Platzman CH. La COVID-19 está ocasionando daño renal y problemas con la diálisis. AARP[Internet].2020 [citado 21 May 2022] Disponible en: https://www.aarp.org/espanol/salud/enfermedades-y-tratamientos/info-2020/como-el-coronavirus-afecta-los-rinones.html
Vaduganathan M, Vardeny O, Michel T, McMurray J, Pfeffer MA, Solomon SD. Renin-angiotensin-aldosterone system inhibitors in patients with COVID-19.N Engl J Med .2020 [citado 11 may 2022];382:1653-9 Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121452
Meghan S, Kassem S. Enfermedad renal y el COVID-19: ¿Cuáles son los riesgos? Massachusetts General Hospital[Internet]. 2020[citado 2021 Ener 22]. Disponible en: https://www.massgeneral.org/es/coronavirus/enfermedad-renal-y-el-COVID-19
Fiani B, Covarrubias C, Desai A, Sekhon M, Jarrah R. A Contemporary Review of Neurological Sequelae of COVID-19. Front Neurol [Internet].2020 [citado 1 Mar 2022];;11:640. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324652/
Lu Y, Li X, Geng D, Mei N, Wu P-Y, Huang C-C, et al. Cerebral Micro-Structural Changes in COVID-19 Patients - An MRI-based 3-month Follow-up Study. EClinical Medicine[Internet]. 2020 [citado 29 Mar 2022];25:100484. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396952/pdf/main.pdf
Fotuhi M, Mian A, Meysami S, Raji CA. Neurobiología de COVID-19. J Alzheimers Dis[Internet]. 2020 [citado 11 Mar 2022]; 76(1):3-19.Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660990
Sociedad Argentina de Pediatría[Internet].Buenos Aires: Sociedad Argentina de Pediatría; 2020. [citado 21 Mar2022]. Compromiso Gastrointestinal por infección por COVID-19. Generalidades. Disponible en: https://www.sap.org.ar/uploads/archivos/general/files_covid-compromiso-gastroint_1587227186.pdf
Padilla PM, Cárdenas BE, Cabrera MC. Impacto del COVID-19 en las enfermedades hepáticas y la salud pública en el Perú. Rev Gastroenterol Perú[Internet]. 2020 [citado 1 Abr 2022];40(2):162-72. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1022-51292020000200162&lng=es.
Lippi G, Favaloro EJ. D-dimer is associated with severity of coronavirus disease 2019: a pooled analysis. Thromb Haemost [Internet]. 2020 [citado 21 Mar 2022];120(5): 876-8. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295300/pdf/10-1055-s-0040-1709650.pdf
Szcześniak D, Gładka A, Misiak B, Cyran A, Rymaszewska J. The SARS-CoV-2 and mental health: From biological mechanisms to so https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384993/
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