Mecanismos de acción hormonal a través de receptores ubicados en la membrana celular

Autores/as

  • Judith Pérez Avila
  • José Luis Valenciaga Rodríguez
  • Alina Acosta
  • Orlando Nicolau Mena
  • Silvia Elena Turcios Tristá
  • Francisco Navaroli Fernández

Palabras clave:

hormonas, membrana celular

Resumen

Se realizó una revisión bibliográfica con el objetivo de exponer y analizar los mecanismos de acción hormonal a través de los receptores hormonales ubicados en la membrana celular, su estructura, la interacción Hormona – Receptor (H-R), los eventos que ocurren a partir de este momento, la participación de segundos mensajero, regulación de las transcripciones de la señal H-R dentro de la célula, su internalización y eventos finales del mecanismo de acción hormonal.

Descargas

Los datos de descargas todavía no están disponibles.

Citas

Fagin JA. Genetic basis of endocrine disease 3: molecular defects in thyroid gland neoplasia. J Clin Endocrinol Metab 1992; 75:1398-400.

Hinkle PM. Introduction to cell signaling: introduction to molecular and cellular research. San Diego, California: The Endocrine Society; 1997.

Naruse M, Naruse K, Nishikawa T, Yoshihara I, Ohsumi K, Suzuki N, et al. Endothelin-3 immunoreactivity in gonadotrophy of the human anterior pituitary. J Clin Endocrinol Metab 1992; 74:968-972.

Mendez P, Azcoitia I, Garcia-Segura LM. Estrogen receptor alpha forms estrogendependent multimolecular complexes with insulin-like growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain. Brain Res Mol Brain Res 2003; 112(1-2):170-6.

Buckbinder L, Robinson RP. The glucocorticoid receptor: molecular mechanism and new therapeutic opportunities. Curr Drug Targets Inflamm Allergy 2002; 1(2):127-36.

Boyan BD, Dean DD, Sylvia VL, Schwartz Z. Steroid hormone action in musculoskeletal cells involves membrane receptor and nuclear receptor mechanisms. Connect Tissue Res 2003;44 Suppl 1:130-5.

Acconcia F, Marino M. Synergism between genomic and non genomic estrogen action mechanisms. IUBMB Life 2003; 55(3):145-50.

Ulloa-Aguirre A, Timossi C. Biochemical and functional aspects of gonadotrophin-releasing hormone and gonadotrophins. Reprod Biomed Online 2000;1(2):48-62.

Buckbinder L, Robinson RP. The glucocorticoid receptor: molecular mechanism and new therapeutic opportunities. Curr Drug Targets Inflamm Allergy 2002; 1(2):127-36.

Escriva Garcia H, Laudet V, Robinson-Rechavi M. Nuclear receptors are markers of animal genome evolution. J Struct Funct Genomics 2003;3(1-4):177-84.

Forsyth IA, Wallis M. Growth hormone and prolactin-molecular and functional evolution. J Mammary Gland Biol Neoplasia 2002; 7(3):291-312.

Chakraborty G, Reddy R, Drivas A, Ledeen RW. Interleukin-2 receptors and interleukin-2- mediated signaling in myelin: activation of diacylglycerol kinase and phosphatidylinositol 3- kinase. Neuroscience. 2003; 122(4):967-73.

Tamrazi A, Katzenellenbogen JA. Site-specific fluorescent labeling of estrogen receptors and structure-activity relationships of ligands in terms of receptor dimer stability. Methods Enzymol 2003; 364:37-53.

Maglich JM, Sluder AE, Willson TM, Moore JT. Beyond the human genome: examples of nuclear receptor analysis in model organisms and potential for drug discovery. Am J Pharmacogenomics 2003; 3(5):345-53.

Joseph EK, Levine JD. Sexual dimorphism in the contribution of protein kinase C isoforms to nociception in the streptozotocin diabetic rat. Neuroscience. 2003; 120(4):907-13.

Grun F, Blumberg B. Identification of novel nuclear hormone receptor ligands by activityguided purification. Methods Enzymol 2003; 364:3-24.

Doughman RL, Firestone AJ, Wojtasiak ML, Bunce MW, Anderson RA. Membrane ruffling requires coordination between type I{alpha} phosphatidylinositol phosphate kinase and rac signaling. J Biol Chem 2003; 278(25):23036-45.

Ben-Chaim Y, Tour O, Dascal N, Parnas I, Parnas H. The M2 muscarinic G-protein-coupled receptor Is voltage-sensitive. J Biol Chem 2003; 278(25):22482-91.

Matre V, Hovring PI, Fjeldheim AK, Helgeland L, Orvain C, Andersson KB, Gautvik KM, Gabrielsen OS. The human neuroendocrine thyrotropin-releasing hormone receptor promoter is activated by the haematopoietic transcription factor c-myb. Biochem J 2003; 372 (Pt 3):851-9.

Rhie DJ, Sung JH, Ha US, Kim HJ, Min DS, Hahn SJ, et al. Endogenous somatostatin receptors mobilize calcium from inositol 1,4,5-trisphosphate-sensitive stores in NG108-15 cells. Brain Res 2003; 975(1-2):120-8.

Vroemen SF, Van der Horst DJ, Van Marrewijk WJ. New insights into adipokinetic hormone signaling. Mol Cell Endocrinol 1998; 141(1-2):7-12.

Quondamatteo F. Assembly, stability and integrity of basement membranes in vivo. Histochem J 2002; 34(8-9):369-81.

Giannella RA, Mann EA. Escherichia coli heat-stable enterotoxin and guanylyl cyclase C: new functions and unsuspected actions. Trans Am Clin Climatol Assoc 2003;114:67-85.

Alzamora R, Marusic ET, Gonzalez M, Michea L. Nongenomic effect of aldosterone on Na+, K+-adenosine triphosphatase in arterial vessels. Endocrinology. 2003; 144(4):1266-72.

Ritchie JW, Shi YB, Hayashi Y, Baird FE, Muchekehu RW, Christie GR, et al. A role for thyroid hormone transporters in transcriptional regulation by thyroid hormone receptors. Mol Endocrinol 2003; 17(4):653-61.

Ko L, Chin WW. Nuclear receptor coactivator thyroid hormone receptor-binding protein (TRBP) interacts with and stimulates its associated DNA-dependent protein kinase. J Biol Chem 2003; 278(13):11471-9.

Secondo A, Sirabella R, Formisano L, D'Alessio A, Castaldo P, Amoroso S, et al. Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the upregulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL receptor activation in GH3 cells. J Neurochem 2003; 84(6):1367-77.

Vasilaki A, Georgoussi Z, Thermos K. Somatostatin receptors (sst2) are coupled to Go and modulate GTPase activity in the rabbit retina. J Neurochem 2000; 84(4):625-32.

Rupprecht R. Neuroactive steroids: mechanisms of action and

neuropsychopharmacological properties. Psychoneuroendocrinology. 2003; 28(2):139-68.

Shah BH, Soh JW, Catt KJ. Dependence of gonadotropin-releasing hormone-induced neuronal MAPK signaling on epidermal growth factor receptor transactivation. J Biol Chem 2003; 278(5):2866-75.

Pedram A, Razandi M, Aitkenhead M, Hughes CC, Levin ER. Integration of the nongenomic and genomic actions of estrogen: membrane-initiated signaling by steroid to transcription and cell biology. J Biol Chem 2002;277(52):50768-75.

Guo YS, Cheng JZ, Jin GF, Gutkind JS, Hellmich MR, Townsend CM. Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signalling pathways: evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor. J Biol Chem 2002; 277(50):48755-63.

Baumann G. Growth hormone binding protein: the soluble growth hormone receptor. Minerva Endocrinol 2002; 27(4):265-76.

Peluso JJ, Fernandez G, Pappalardo A, White BA. Membrane-initiated events account for progesterone's ability to regulate intracellular free calcium levels and inhibit rat granulosa cell mitosis. Biol Reprod 2002; 67(2):379-85.

Segars JH, Driggers PH. Estrogen action and cytoplasmic signaling cascades: part I: membrane-associated signaling complexes. Trends Endocrinol Metab 2002; 13(8):349-54.

Levin ER. Cellular functions of plasma membrane estrogen receptors. Steroids. 2002; 67 (6):471-5.

Kock CP de, Wierda KD, Bosman LW, Min R, Koksma JJ, Mansvelder HD, et al. Somatodendritic secretion in oxytocin neurons is upregulated during the female reproductive cycle. J Neurosci 2003; 23(7):2726-34.

Losel R, Feuring M, Wehling M. Non-genomic aldosterone action: from the cell membrane to human physiology. J Steroid Biochem Mol Biol 2002; 83(1-5):167-71.

Papaconstantinou AD, Umbreit TH, Goering PL, Brown KM. Effects of 17 alphamethyltestosterone on uterine morphology and heat shock protein expression are mediated through estrogen and androgen receptors. J Steroid Biochem Mol Biol 2002; 82(4-5):305-14.

Chambliss KL, Shaul PW. Estrogen modulation of endothelial nitric oxide synthase. Endocr Rev 2002; 23(5):665-86.

Heinlein CA, Chang CF. The roles of androgen receptors and androgen-binding proteins in nongenomic androgen actions. Mol Endocrinol 2002;16(10):2181-7.

Descargas

Publicado

10-06-2005

Cómo citar

1.
Pérez Avila J, Valenciaga Rodríguez JL, Acosta A, Nicolau Mena O, Turcios Tristá SE, Navaroli Fernández F. Mecanismos de acción hormonal a través de receptores ubicados en la membrana celular. Medimay [Internet]. 10 de junio de 2005 [citado 22 de diciembre de 2024];11(1):38-47. Disponible en: https://medimay.sld.cu/index.php/rcmh/article/view/153

Número

Sección

Artículos de Revisión

Artículos más leídos del mismo autor/a

Artículos similares

También puede {advancedSearchLink} para este artículo.